In compliance with current regulations, let us know which audience you belong to:
We’re proud to announce our Light Modulation™ LLLT technology has recently been studied in a piece of research in combination therapy with OPE™ IPL tech.
The randomized, controlled, blinded study evaluates the efficacy of intense pulsed light (IPL) therapy with low‐level light therapy (LLLT) in the treatment of meibomian gland dysfunction (MGD) and evaporative dry eye (EDE) compared to a control group.
Hundred patients with MGD and EDE were randomized into control (50 subjects, 100 eyes) and study group (50 subjects, 100 eyes). The study group underwent three sittings of IPL with LLLT 15 days apart and were followed up 1 month and 2 months after the last treatment sitting. The control group underwent sham treatment and was followed up at the same intervals.
The study, published on IJO, the Indian Journal of Ophthalmology, by Sharon D’Souza (MD), Rohit Shetty (MD, PhD) et al., has shown the clinical efficacy of combined therapy of intense pulsed light (OPE™ IPL) with Low‑Level Light Therapy (LM™ LLLT) in treating meibomian gland dysfunction (MGD) and evaporative dry eye (EDE).
It was demonstrated a significant improvement in symptomatology along with improvement in tear film parameters like tear breakup time, and in ocular symptoms, by significant reduction in OSDI after three treatment sessions. The significantly improved tear film stability in this study suggests that OPE™ IPL + LM™ LLLT influences the meibomian gland outflow both in the quantity and quality of meibum secreted.
Directly citing the conclusions of the paper:
The Intense intense pulsed light (OPE™ IPL) with Low‑Level Light Therapy (LM™ LLLT) has shown good results for the treatment of meibomian gland dysfunction (MGD) and evaporative dry eye (EDE). Cumulative effects of sequential sessions have been evaluated and found to have good results. In addition, no adverse effects like postprocedure skin pigmentation or burns were noted during this study.
SOURCE
D’Souza, Sharon; James, Edwin; Koul, Ameeta; Modak, Durgalaxmi; Kundu, Gairik; Shetty, Rohit. A randomized controlled study evaluating outcomes of intense pulsed light and low-level light therapy for treating meibomian gland dysfunction and evaporative dry eye. Indian Journal of Ophthalmology 71(4):p 1608-1612, April 2023.
> Link to Issue
> Link to Paper
> Link to Full Bibliography
About Espansione Group
Espansione Group is a pioneer in the medtech industry, on a mission to develop and market innovative, non-invasive solutions for prevention and management of conditions in ophthalmology and beyond.
The company’s certified medical solutions leverage proprietary technologies such as Light Modulation™ Low-level Light Therapy (LM™ LLLT) photobiomodulation (PBM), with an ambition to redefine standards of care by expanding on their applications, with a constant commitment to science, research and development, and customer excellence.
Strategic partnerships with the industry, a strong commitment to scientific excellence and a will to shape the future have enabled Espansione Group’s advanced medical technologies to be present in over 50 countries, serving thousands healthcare providers worldwide.
For more information, visit www.espansionegroup.it
Espansione Group Press Office
press@espansione.it
© 2023 Espansione Group, All Rights Reserved
Posted on May 5th, 2025 in Newsroom