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Light Science

LM® LLLT is our patented photobiomodulation technology—it works by triggering endogenous heating of both eyelids, stimulating ATP production.

Three frequencies.
Endless possibilities.

Light Modulation® Low-level Light Therapy can be leveraged employing three different light frequencies—each with its own unique benefits and use cases.

Red Light
Used for Inflammation Reduction and ATP Production Stimulus
Key facts on Red LM® LLLT:
  • Improves cells metabolism due to increased ATP production within mitochondria
  • Reduces inflammation by regulating anti-oxidant defenses and reducing oxidative stress
  • Light-induced activation of transcription factors and signaling pathways
  • When a 15-minute treatment is applied, the total fluence in the treated area is 100 Joules/cm2
  • The photobiomodulation device has an emission power of 100 mW/cm2
Use Cases in Ophthalmology

DED/MGD, Chalazion, Stye, Sjögren’s Syndrome, Blepharitis, Ocular Surgery, Ectropion

Blue Light
Used for Bacteria Elimination
Key facts on Blue LM® LLLT:
  • Blue light energy is absorbed by molecules called porphyrins within bacteria and photosensitization occurs
  • Exposure to the light can result in photodynamic inactivation, a process in which bacteria are killed by light
  • The porphyrin molecules generate singlet oxygen radicals that damage or disrupt the cell wall of a variety of gram-positive bacteria and lead to cell death
  • The relatively weak defense mechanism in bacteria against singlet oxygen induces damage, contributing to the high efficiency of the photodynamic inactivation
Use Cases in Ophthalmology

Demodex, Blepharitis, Rosacea

Yellow Light
Used for Drainage and Swelling Reduction
Key facts on Yellow LM® LLLT:
  • Yellow light acts on mitochondrial respiration and increases ATP production
  • Promotes the release of nitric oxide to assist in neuro-transmission and tissue repair
  • Decreases the inflammatory response by reducing the oedema
  • Increases skin elasticity and decreases metalloproteinases activity
Use Cases in Ophthalmology

Post-Invasive Surgery (e.g., Blepharoplasty)

Scientific Coverage
Impact on tear breakup time
Impact on ocular surface disease index (i.e., OSDI)
STONECIPHER, Karl, et al. Combined low level light therapy and intense pulsed light therapy for the treatment of meibomian gland dysfunction. Clinical Ophthalmology, 2019
Studies show that tear production quality increases dramatically, as the treatment nearly doubles tear breakup time, resulting in immediate relief of symptoms.

And consequently, the treatment improved by 10 points or more the patient’s ocular surface disease index—i.e., OSDI Index, in over 70% of cases, with only one treatment.

Endogenous Heating

Recently run thermography studies have shown upper and lower meibomian glands being simultaneously, directly treated at optimal temperature—i.e., 42°C, through LM® LLLT.

Light Modulation® LLLT triggers endogenous heating to both eyelids, stimulating ATP production and removing blockage from meibomian glands preventing proper functioning—and it does so with zero discomfort for the patient.

Courtesy of Dr. Heiko Pult—OD, PHD
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